News Update on Free Radical Scavenging Research: Aug – 2019

Free radical scavenging activities of mushroom polysaccharide extracts

The superoxide and radical scavenging activities of eight mushroom growth carbohydrate extracts were investigated exploitation phenazin methosulphate-NADH-nitroblue tetrazolium system and ascorbic acid-Cu2+-cytochrome C system severally. The results showed that six of eight mushroom carbohydrate extracts had superoxide and radical scavenging activities. The supermolecule content of the carbohydrate extracts gave the impression to contribute a right away result on atom scavenging activity. [1]

Free radical scavenging activity of curcuminoids

Three natural curcuminoids (curcumin (CAS 458-37-7), demethoxycurcumin, bisdemethoxycurcumin) and acetylcurcumin were compared for his or her ability to scavenge superoxide radicals and to move with one,1-diphenyl-2-picryl-hydrazyl (DPPH) stable free radicals. The results showed that curcumin is that the most potent scavenger of superoxide radicals followed by demethoxycurcumin and bisdemethoxycurcumin. Acetylcurcumin was inactive. Interaction with DPPH showed an analogous activity profile. [2]

Iridoid Glucosides with Free Radical Scavenging Properties from Fagraea blumei

Four new iridoid glucosides 1–4, named blumeosides A–D, were isolated from the methanolic stem‐bark extract of Fagraea blumei G. DON. (Loganiaceae). They were in the midst of the benzyl‐alcohol by-product di‐O‐methylcrenatin (5) and also the flavone C‐glucoside swertisin (6). The structures of 1–4 were established by chemical analysis strategies, together with FAB‐MS, and 1H‐ and 13C‐NMR, and by alkalescent reaction. Blumeosides A (1) and C (3) area unit 10‐O‐(2,5‐dihydroxytercphthalo) adoxosidic acid and 10‐O‐(2‐hydroxyterephthalo)adoxosidic acid, severally. [3]

Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root

The extract from Smilax china root has been used as healthful remedy and according to retain antimicrobial and antimutagenic acitivities. during this study, a attainable presence of inhibitor activity of Smilax china root extract was investigated. wood spirit extract (Me) disclosed the presence of high one,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity (IC50 seven.4 µg/ml) and protecting property of cell’s viability. more fractionation with varied solvent extraction and assay showed high levels of DPPH radical scavenging activity within the ester, butyl alcohol and water extracted fractions. [4]

Phytochemical Profile and Free Radical Scavenging Activities of Methanol Extract of Green Pea

The legume, pea (Pisum sativum) is sometimes consumed as a vegetable. Phytochemical screening of its wood alcohol extract showed that it contains terpenoids, resins, viscus glycosides, steroids, saponins, phenols and flavonoids. Quantitative phytochemical estimation in (20/mg) unconcealed that it contains Saponins thirteen.4±0.11, Flavonoids ten.4±0.089, Phenols 9.8±0.063 and steroids seven.2±0.075. [5]


[1] Liu, F., Ooi, V.E.C. and Chang, S.T., 1997. Free radical scavenging activities of mushroom polysaccharide extracts. Life sciences, 60(10), pp.763-771. (Web Link)

[2] Sreejayan, N. and Rao, M.N., 1996. Free radical scavenging activity of curcuminoids. Arzneimittel-forschung, 46(2), pp.169-171. (Web Link)

[3] Cuendet, M., Hostettmann, K., Potterat, O. and Dyatmiko, W., 1997. Iridoid glucosides with free radical scavenging properties from Fagraea blumei. Helvetica Chimica Acta, 80(4), pp.1144-1152. (Web Link)

[4] Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root
Si Eun Lee, Eun Mi Ju & Jeong Hee Kim
Experimental & Molecular Medicinevolume 33, pages263–268 (2001) (Web Link)

[5] Chibuzo Carole, N., Nurudeen Olajide, R. and Hassan, S. (2018) “Phytochemical Profile and Free Radical Scavenging Activities of Methanol Extract of Green Pea”, International Journal of Biochemistry Research & Review, 21(3), pp. 1-8. doi: 10.9734/IJBCRR/2018/39855. (Web Link)

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