Latest Research on Gastrointestinal Diseases: Nov – 2019

Protection from gastrointestinal diseases with the use of probiotics

Probiotics square measure nonpathogenic microorganisms that, once eaten, exert a positive influence on the health or physiology of the host. they’ll influence enteric physiology either directly or indirectly through modulation of the endogenous system or system. The results that are shown with a ample level of proof to modify probiotics to be used as treatments for duct disturbances square measure 1) the nice tolerance of yoghurt compared with milk in subjects with primary or secondary disaccharide maldigestion, 2) the employment of fungus genus boulardii and Enterococcus faecium SF sixty eight to stop or shorten the length of antibiotic-associated symptom, 3) the employment of S. boulardii to stop more repeat of eubacteria difficile–associated symptom, and 4) the employment of hard milks containing eubacteria rhamnosus GG to shorten the length of symptom in infants with reovirus redness (and most likely conjointly in inflammatory disease of alternative causes). [1]

Probiotics and gastrointestinal diseases

There is increasing proof indicating health advantages by consumption of foods containing microorganisms, i.e. probiotics. variety of clinical trials are performed to guage the consequences within the hindrance and treatment of canal diseases caused by unhealthful microorganisms or by disturbances in the traditional microflora. canal infections caused by Helicobacter pylori, traveller’s symptom, reovirus symptom, antibiotic‐associated symptom (AAD) and eubacterium difficile‐induced diarrhoea are conditions that are studied. There also are studies performed on the preventive result of probiotics on radiation‐induced symptom and diarrhoea in tube‐fed patients. [2]

AGA technical review on osteoporosis in gastrointestinal diseases

Osteoporosis is progressively recognized as a supply of serious incapacity, AN awareness that has prompted clinicians to actively pursue the designation among risky patients. Fractures have a noticeable associated morbidity, negative impact on quality of life, and each direct and indirect prices. Hip fractures have long been related to AN exaggerated morbidity, however solely recently has excessive mortality conjointly been shown to accompany non–hip fractures and low bone mass.1, 2, three The excessive mortality related to fractures is essentially confined to senior males and biological time females. several patients with canal (GI) disorders in danger for pathology square measure young, and these information might not apply to them. [3]

Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank

Depression affects all aspects of associate individual’s life however proof with reference to the causative effects on health is proscribed. we tend to used data from 337,536 UK Biobank participants and performed hypothesis-free phenome-wide association analyses between major depression (MDD) genetic risk score (GRS) and 925 illness outcomes. GRS–disease outcome associations passing the multiple-testing corrected significance threshold. [4]

Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Disorders in the Western Middle Atlas Region (Morocco)

Aims: The alimentary canal is one among the foremost vital organs of the physical structure and is prone to completely different diseases. accessible medicine typically have low effectualness or are related to several adverse effects. Therefore, various medicine are necessary to treat duct complications. This study meant to spot healthful plants within the Western Middle Atlas, Morocco, that may have an effect on duct disorders.

Place and period of Study: Field studies were dole out more or less over a period of 2 years (2013-2014).

Methodology: throughout the sector visits, the knowledge was collected through interviews, together with varied knowledge obtained from native healers and ancient medication men, herbalists, shepherds, patients and older persons. [5]

Reference

[1] Marteau, P.R., Vrese, M.D., Cellier, C.J. and Schrezenmeir, J., 2001. Protection from gastrointestinal diseases with the use of probiotics. The American journal of clinical nutrition, 73(2), (Web Link)

[2] Sullivan, Å. and Nord, C.E., 2005. Probiotics and gastrointestinal diseases. Journal of internal medicine, 257(1), (Web Link)

[3] Bernstein, C.N., Leslie, W.D. and Leboff, M.S., 2003. AGA technical review on osteoporosis in gastrointestinal diseases. Gastroenterology, 124(3), (Web Link)

[4] Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank
Anwar Mulugeta, Ang Zhou, Catherine King & Elina Hyppönen
Molecular Psychiatry (2019) (Web Link)

[5] Fatiha, E. A., Nazha, A., Fouad, Z., Ouafae, B., Maryama, H. and Lahcen, Z. (2018) “Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Disorders in the Western Middle Atlas Region (Morocco)”, Annual Research & Review in Biology, 28(2), (Web Link)

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