Skin disease and handicap: An analysis of the impact of skin conditions

This research sought to quantify the handicapping effect of skin conditions in a far more rigorous way than had previously been attempted. One hundred people who had attended a hospital outpatient clinic during a specified period for treatment of their acne, psoriasis or eczema were interviewed in their homes. [1]

Oxidative Stress in the Pathogenesis of Skin Disease

Skin is the largest body organ that serves as an important environmental interface providing a protective envelope that is crucial for homeostasis. On the other hand, the skin is a major target for toxic insult by a broad spectrum of physical (i.e. UV radiation) and chemical (xenobiotic) agents that are capable of altering its structure and function. Many environmental pollutants are either themselves oxidants or catalyze the production of reactive oxygen species (ROS) directly or indirectly. [2]

The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions

The Global Burden of Disease (GBD) Study 2010 estimated the GBD attributable to 15 categories of skin disease from 1990 to 2010 for 187 countries. For each of the following diseases, we performed systematic literature reviews and analyzed resulting data: eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin diseases, impetigo, abscess, and other bacterial skin diseases, cellulitis, viral warts, molluscum contagiosum, and non-melanoma skin cancer. [3]

Experiences and Perceptions of People with Chronic Skin Disease: A Qualitative Study

Aims: Skin diseases are a common reason for consulting the general practitioner (GP). Few studies have been conducted that explore the topic of chronic skin disease from the patient’s perspective. The aim of this paper was to investigate experiences and perceptions of people with chronic skin diseases and their respective pathways into the health care system. [4]

Evaluation of Reaction Pattern of Skin Diseases in Oman: A Study Based on Immunofluorescence and Light Microscopy Investigation Only

Aims: The aim of this study was to evaluate various reaction pattern of skin diseases in Oman using immunofluorescence and light microscopy investigation only. Methodology: A total of 187 skin biopsies were retrospectively analyzed at Sultan Qaboos University Hospital between 2006 and 2010. The presence of immune-reactants (IgA, IgG, IgM, C3 and Fibrin) and the final diagnosis by heamatoxylin and eosin stain in skin biopsy were investigated. [5]


[1] Jowett, S. and Ryan, T., 1985. Skin disease and handicap: an analysis of the impact of skin conditions. Social science & medicine20(4), pp.425-429.

[2] Bickers, D.R. and Athar, M., 2006. Oxidative stress in the pathogenesis of skin disease. Journal of Investigative Dermatology126(12), pp.2565-2575.

[3]  Hay, R.J., Johns, N.E., Williams, H.C., Bolliger, I.W., Dellavalle, R.P., Margolis, D.J., Marks, R., Naldi, L., Weinstock, M.A., Wulf, S.K. and Michaud, C., 2014. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions. Journal of Investigative Dermatology134(6), pp.1527-1534.

[4]  Esch, M., Rübsam, M.L., Baum, E. and Bösner, S., 2015. Experiences and perceptions of people with chronic skin disease: a qualitative study. Journal of Advances in Medicine and Medical Research, pp.106-113.

[5]  Alwahaibi, N.Y., Alabri, G.K., Alsinawi, S.S. and Qureshi, A., 2014. Evaluation of Reaction Pattern of Skin Diseases in Oman: A Study Based on Immunofluorescence and Light Microscopy Investigation Only. Journal of Advances in Medicine and Medical Research, pp.5033-5042.


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