Latest Research News on Calotropis Procera Research: Sep – 2019

Anthelmintic Activity of Latex of Calotropis procera

The crude latex of Calotropis procera was evaluated for anthelmintic activity mistreatment adult earthworms. each recent furthermore as binary compound extracts of dried latex exhibited a dose-dependent inhibition of spontaneous motility (paralysis) and induced responses to pin-prick. With higher doses (100mg/ml of binary compound extract of dry latex and 100 percent recent latex) the results were comparable that of three helminthic. However, there was no final recovery within the case of worms treated with latex in distinction to helminthic with that the palsy was reversible and also the worms recovered utterly inside six hours. [1]

Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats

Hydro-ethanolic extract (70%) of Calotropis procera flowers was ready and tested for its hepatoprotective impact against paracetamol-induced infectious disease in rats. Alteration within the levels of organic chemistry markers of viscus injury like SGPT, SGOT, ALP, bilirubin, cholesterin, lipoprotein and tissue GSH were tested in each treated and untreated teams. Paracetamol (2 g/kg) has increased the SGPT, SGOT, ALP, animal pigment and cholesterin levels and reduced the bodily fluid levels of lipoprotein and tissue level of GSH. Treatment with hydro-ethanolic extract of C. procera flowers (200 mg/kg and four hundred mg/kg) has brought back the altered levels of organic chemistry markers to the close to traditional levels within the dose dependent manner. [2]

Pharmacological Studies on Aerial Parts of Calotropis Procera

The stewing of the aerial a part of Calotropis procera is often employed in Saudi ancient medication for the treatment of type of diseases as well as fever, joint pain, muscular spasm and constipation. this investigation was undertaken to substantiate its claimed activity in ancient medication. The plant product extract of the plant was tested on laboratory animals for its antipyretic, analgesic, medicinal drug, medication, purgative and relaxant activities. The results of this study showed a major antipyretic, analgesic and fascicle block activity. [3]

Transcriptome and Metabolite analysis reveal candidate genes of the cardiac glycoside biosynthetic pathway from Calotropis procera

Calotropis procera may be a healthful plant of large importance because of its pharmaceutical active parts, particularly internal organ glycosides (CG). As genomic resources for this plant are restricted, the genes concerned in CG synthesis pathway stay mostly unknown until date. Our study on stage and tissue specific matter accumulation showed that CG’s were maximally accumulated in stems of three month previous seedlings. [4]

Proximate Analysis and Time Killing Kinetics of Calotropis procera Extracts on Some Selected Pathogens

The proximate composition and time killing dynamics of the leaf and stem extracts of Calotropis procera were administered. The proximate composition showed wetness content of (10.45 and 9.78%), supermolecule (16.20 and 8.15%), fat (1.99 and 0.96%), ash (14.32 and 6.39%), crude fibre (6.73 and 23.23%) and sugar (49.49 and 51.49%) for leaf and also the stem severally. Twelve unhealthful bacterium and 5 fungi species were obtained from the Department of biology, Federal University of Technology, Akure, Ondo-State and written cultures of the organisms were collected from National Institute of Medical analysis (American sort culture assortment centre (ATCC), USA). [5]

Reference

[1] Shivkar, Y.M. and Kumar, V.L., 2003. Anthelmintic activity of latex of Calotropis procera. Pharmaceutical biology, 41(4), (Web Link)

[2] Ramachandra, S.S., Quereshi, A.A., Viswanath, A.S., Patil, T., Prakash, T., Prabhu, K. and Veeran, A.G., 2007. Hepatoprotective activity of Calotropis procera flowers against paracetamol-induced hepatic injury in rats. Fitoterapia, 78(7-8), (Web Link)

[3] Mossa, J.S., Tariq, M., Mohsin, A., Ageel, A.M., Al-Yahya, M.A., Al-Said, M.S. and Rafatullah, S., 1991. Pharmacological studies on aerial parts of Calotropis procera. The American journal of Chinese medicine, 19(03n04), (Web Link)

[4] Transcriptome and Metabolite analysis reveal candidate genes of the cardiac glycoside biosynthetic pathway from Calotropis procera
Akansha Pandey, Vishakha Swarnkar, Tushar Pandey, Piush Srivastava, Sanjeev Kanojiya, Dipak Kumar Mishra & Vineeta Tripathi
Scientific Reports volume6, Article number: 34464 (2016) (Web Link)

[5] S. Asoso, O., Oladunmoye, K. O. and Ogundare, A. O. (2018) “Proximate Analysis and Time Killing Kinetics of Calotropis procera Extracts on Some Selected Pathogens”, European Journal of Medicinal Plants, 22(2), (Web Link)

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